Spatial Agency: Other Ways Of Doing Architecture

Silica nanoparticles could be used to repair damaged teeth

Researchers at the University of Birmingham have shown how the development of coated silica nanoparticles could be used in restorative treatment of sensitive teeth and preventing the onset of tooth decay.

The study, published in the Journal of Dentistry, shows how sub-micron silica particles can be prepared to deliver important compounds into damaged teeth through tubules in the dentine.

The tiny particles can be bound to compounds ranging from calcium tooth building materials to antimicrobials that prevent infection.

Professor Damien Walmsley, from the School of Dentistry at the University of Birmingham, explained, “The dentine of our teeth have numerous microscopic holes, which are the entrances to tubules that run through to the nerve. When your outer enamel is breached, the exposure of these tubules is really noticeable. If you drink something cold, you can feel the sensitivity in your teeth because these tubules run directly through to the nerve and the soft tissue of the tooth.”

“Our plan was to use target those same tubules with a multifunctional agent that can help repair and restore the tooth, while protecting it against further infection that could penetrate the pulp and cause irreversible damage.”

The aim of restorative agents is to increase the mineral content of both the enamel and dentine, with the particles acting like seeds for further growth that would close the tubules.

Previous attempts have used compounds of calcium fluoride, combinations of carbonate-hydroxypatite nanocrystals and bioactive glass, but all have seen limited success as they are liable to aggregate on delivery to the tubules. This prevents them from being able to enter the opening which is only 1 to 4 microns in width.

However, the Birmingham team turned to sub-micron silica particles that had been prepared with a surface coating to reduce the chance of aggregation.

When observed using high definition SEM (Scanning Electron Microsopy), the researchers saw promising signs that suggested that the aggregation obstacle had been overcome.

Professor Zoe Pikramenou, from the School of Chemistry at the University of Birmingham, said, “These silica particles are available in a range of sizes, from nanometre to sub-micron, without altering their porous nature. It is this that makes them an ideal container for calcium based compounds to restore the teeth, and antibacterial compounds to protect them. All we needed to do was find the right way of coating them to get them to their target.  We have found that different coatings does change the way that they interact with the tooth surface.”

“We tested a number of different options to see which would allow for the highest level particle penetration into the tubules, and identified a hydrophobic surface coating that provides real hope for the development of an effective agent.”

Our next steps are to optimise the coatings and then see how effective the particles are blocking the communication with the inside of the tooth.  The ultimate aim is to provide relief from the pain of sensitivity.

University of Birmingham

Nanotechnology World Association

Michelle Obama launches #62MillionGirls to fight for girls’ education

Michelle Obama has unveiled a new campaign focusing on the tens of millions of girls around the world who lack access to any kind of education. "Right now, 62 million girls are not in school,“ the first lady told the Global Citizens Festival. “And what’s important to know is that these are our girls. They deserve the same chances to get an education as my daughters and your daughters and all of our children.“ Celebrities, politicians and other Twitter users were quick to jump on the hashtag.

How To Build More Resilient Cities

New Perovskite “Soccer Ball” Solar Cell Could Drive Down Costs

Low cost perovskite solar cell with tandem architecture and low cost fabrication…

Follow me on Twitter and Google.

Photo credit (cropped): “Highly efficient semi-transparent Perovskite solar cell partners with CIGS thin film solar cell” via Empa Pictures/flickr.com.

This came across my desk this morning in the course of philanthropic research, and it’s a fascinating portrait primarily of the head of a charitable organization that serves his own community (the blind and visually impaired) but also a mixed-message reconstruction of a man who mysteriously bequeathed $125M – fifteen times the charity’s operating budget – to an organization that never knew his name. 

(A more-or-less transcript of the podcast is also available below the player.)

When Firms Become Persons and Persons Become Firms: outstanding lecture

UC Berkeley Political Scientist Wendy Brown came to the London School of Economics last week to discuss her book Undoing the Demos, and her lecture (MP3) is literally the best discussion of how and why human rights are being taken away from humans and given to corporations.

Brown looks at the human rights enumerated in the US Bill of Rights, and how they have been interpreted in successive Supreme Court rulings like Hobby Lobby (corporations are people whose religious freedom entitles them to deny contraception to their workers) and Citizens United (corporations are people and have the free speech right to buy politicians). She suggests that these have been misread as merely conservative/business-oriented thinking gaining influence, and that rather, they are best understood as an ongoing project that grants personhood to companies at the expense of real people.

Brown speaks for more than an hour with almost no poli-sci/econ jargon, building elegant, beautiful arguments that should be accessible to anyone. If you listen to anything this weekend, make it this.

Neoliberal rationality — ubiquitous today in statecraft and the workplace, in jurisprudence, education, and culture — remakes everything and everyone in the image of homo oeconomicus. What happens when this rationality transposes the constituent elements of democracy into an economic register? In vivid detail, Wendy Brown explains how democracy itself is imperiled. The demos disintegrates into bits of human capital; concerns with justice cede to the mandates of growth rates, credit ratings, and investment climates; liberty submits to the imperative of human capital appreciation; equality dissolves into market competition; and popular sovereignty grows incoherent. Liberal democratic practices may not survive these transformations. Radical democratic dreams may not either.

In an original and compelling theoretical argument, Brown explains how and why neoliberal reason undoes the political form and political imaginary it falsely promises to secure and reinvigorate. Through meticulous analyses of neoliberalized law, political practices, governance, and education, she charts the new common sense. Undoing the Demos makes clear that, far from being the lodestar of the twenty-first century, a future for democracy depends upon it becoming an object of struggle and rethinking.

Undoing the Demos: Neoliberalism’s Stealth Revolution [Wendy Brown/Zone Books]

When Firms Become Persons and Persons Become Firms: neoliberal jurisprudence in Burwell v. Hobby Lobby Stores [LSE]

MP3

A new online platform to promote women’s economic empowerment is here! UN Women and the Government of Canada recently launched an online platform, the Global Knowledge Gateway for Women’s Economic Empowerment, which aims to re-vitalize women’s economic empowerment by building connections, and providing users with tools and resources necessary to be empowered. Get the link to this exciting new initiative here: www.empowerwomen.org

Digital mapping + solar = sustainable cities?

A new tool combines Google satellite imagery with light detection and ranging data, calculating the potential hourly solar energy production of a city.

One of the World’s Most Powerful Central Bankers Is Worried About Climate Change

The governor of the Bank of England warns about risks to global financial stability.

A new speech about climate change is fascinating both for what it says and who said it.

Mark Carney, the governor of the Bank of England, declared that the warming climate presented major risks for the global economy and global financial stability, and that businesses and regulators needed to move more quickly to try to contain the potential economic damage even though it may seem uncertain and far off.

His warning, delivered in a 4,400-word speech with ample footnotes on Tuesday, is the latest example of how climate change has moved beyond theoretical scientific debates to the start of practical planning for safeguarding the economy and business.

“We don’t need an army of actuaries to tell us that the catastrophic impacts of climate change will be felt beyond the traditional horizons of most actors — imposing a cost on future generations that the current generation has no direct incentive to fix,” he said. “In other words, once climate change becomes a defining issue for financial stability, it may already be too late.”

Mr. Carney calls the economic challenges around climate the “tragedy of the horizon,” in contrast to the long-noted economic phenomenon of the “tragedy of the commons.” That is, the costs of a warming climate come on a time scale and with an uncertainty that go beyond the usual multiyear business cycle, beyond political cycles of presidential and parliamentary elections, or as he puts it, beyond “the horizon of technocratic authorities, like central banks, who are bound by their mandates.”

It might seem odd for a central banker to be talking about a long-term problem of global climate, all the more so when the global economy is looking rather shaky. After all, the job is typically to worry about price inflation and the banking system.

But if you back up and define a central banker’s job a little more broadly — to worrying about the economy and the stability of the financial system writ large — it quickly becomes clear why climate matters.

Good read from NYTimes.